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KMID : 1139819970010010211
Journal of Dong - Eui Oriental Medicine
1997 Volume.1 No. 1 p.211 ~ p.219
Cytotoxicity of Patriniae Herba on Human cancer cell-lines
Shin Dae-Chul

Kim Young-Kyun
Kwon Jung-Nam
Han Jong-Hyun
Kim Jae-Seok
Kim Jae-Seop
Abstract
The purpose of this study was to investigate effect of water extract of Patriniae Herba on the poliferation of human cancer cell-lines.

The effects of Patriniae Herba on the poliferation of A43l, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay,

The results were as follows;

1. Patriniae Herbs did not effect A43l, HeLa, MOLT-4, K562 cells.

2. The cytotoxicity of mitomycin C on MOLT-4 cells was increased by the combination of Patriniae Herba.

3. Patriniae Herba inhibited the proliferation of Balb/c 3T3 cells.

4. Patriniae Herba stimulated the proliferation of thymocytes.

5. Patriniae Herba stimulated the proliferation of splenocytes.

6. Patriniae Herba stimulated the proliferation of human lymphocytes.
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